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In Vivo Imaging of the Programmed Death Ligand 1 by 18F PET

6 Jun 2017

Abstract excerpt

Programmed death ligand 1 (PD-L1) is an immune regulatory ligand that binds to the T-cell immune check point programmed death 1. Tumor expression of PD-L1 is correlated with immune suppression and poor prognosis. It is also correlated with therapeutic efficacy of programmed death 1 and PD-L1 inhibitors. In vivo imaging may enable real-time follow-up of changing PD-L1 expression and heterogeneity evaluation of...

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PMID: 28588151
DOI: 10.2967/jnumed.117.191718

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