Article

Enhancing the invasive traits of breast cancers by CYP1B1 via regulation of p53 to promote uPAR expression

2022-07-15

Abstract excerpt

<title>Abstract</title> <p>Human cytochrome P450 1B1 (CYP1B1) catalyzes estrogen metabolism to produce metabolites that promote the progression of breast cancer. Since the invasive properties of cancer cells cause cancer relapse, which dramatically reduces patient survival, we investigated the new pro-invasive mechanism involving CYP1B1 in breast cancer. Exploring clinical data from invasive breast cancer patient...

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Literature Corpus work: fe1629af-ebea-586c-a3c7-92867911b865
DOI: 10.21203/rs.3.rs-1830306/v1

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