Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutant TP53 interacts with BCAR1 to contribute to cancer cell invasion.

British journal of cancer - 1 Jan 2021

Guo Alvin Kunyao, Itahana Yoko, Seshachalam Veerabrahma Pratap, Chow Hui Ying, Ghosh Sujoy, Itahana Koji

Abstract excerpt

BACKGROUND: Mutant TP53 interacts with other proteins to produce gain-of-function properties that contribute to cancer metastasis. However, the underlying mechanisms are still not fully understood. METHODS: Using immunoprecipitation and proximity ligation assays, we evaluated breast cancer anti-estrogen resistance 1 (BCAR1) as a novel binding partner of TP53R273H, a TP53 mutant frequently found in human cancers....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Tumor
Share to Mutation
Share to Neoplasm Invasiveness

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 33144694
DOI: 10.1038/s41416-020-01124-9
PMCID: PMC7782524

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutant TP53 interacts with BCAR1 to contribute to cancer cell invasion.PMID 33144694Read ↗

Mutants TP53 p.R273H and p.R273C but not p.R273G enhance cancer cell malignancy.Semantic proximity Read ↗

Multidimensional analysis to elucidate the possible mechanism of bone metastasis in breast cancerSemantic proximity Read ↗

A TP73‐AS1/miR‐200a/ZEB1 regulating loop promotes breast cancer cell invasion and migrationSemantic proximity Read ↗

MiR-519e-5p regulates malignant phenotype of breast cancer cells through binding to CTPS1.Semantic proximity Read ↗

Characterization of the Translationally Controlled Tumor Protein (TCTP) Interactome Reveals Novel Binding Partners in Human Cancer CellsSemantic proximity Read ↗

Enhancing the invasive traits of breast cancers by CYP1B1 via regulation of p53 to promote uPAR expressionSemantic proximity Read ↗

Identification of tyrosine-phosphorylated proteins associated with metastasis and functional analysis of FER in human hepatocellular carcinoma cellsSemantic proximity Read ↗

Raf Kinase Inhibitory Protein (RKIP) as a Metastasis Suppressor: Regulation of Signaling Networks in CancerSemantic proximity Read ↗

The long noncoding RNA AATBC promotes breast cancer migration and invasion by interacting with YBX1 and activating the YAP1/Hippo signaling pathwaySemantic proximity Read ↗

The interplay among MAP3K1 and SOX2 regulated metastasis by MAPK signaling pathway through interaction with KLF4 in triple-negative breast cancerSemantic proximity Read ↗

LRP1B: A Giant Lost in Cancer TranslationSemantic proximity Read ↗

Ras Suppressor-1 (RSU1) in Cancer Cell Metastasis: A Tale of a Tumor Suppressor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.