Article

Human Cancers Deriving from Either Genetic or Lifestyle Factors, Are Initiated by the Damage of Estrogen Signaling

2025-10-28

Abstract excerpt

<h4>Background: </h4> Genetic studies justified that germline BRCA1 gene mutation is the origin of highly increased cancer risk. Clinical studies suggested that increased cancer risk in type-2 diabetes maybe attributed to unhealthy lifestyle factors and bad habits. Purpose. Patients with either BRCA1 gene mutation or type-2 diabetes similarly exhibit increased cancer risk, insulin resistance and fertility disorder...

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Literature Corpus work: fe1480b0-da43-5557-b6d6-bc3c03aece32
DOI: 10.20944/preprints202510.2109.v1

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