Article

Robust and Interpretable PAM50 Reclassification Exhibits Survival Advantage for Myoepithelial and Immune Phenotypes

2018-11-28

Abstract excerpt

We introduce a classification of breast tumors into 7 classes which are more clearly defined by interpretable mRNA signatures along the PAM50 gene set than the 5 traditional PAM50 intrinsic subtypes. Each intrinsic subtype is partially concordant with one of our classes, and the 2 additional classes correspond to division of the classes concordant with the Luminal B and the Normal intrinsic subtypes along expressi...

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Identifiers and source

Literature Corpus work: fdbaa223-e9bf-5f3d-8383-f2b48bc9bc70
DOI: 10.1101/480723

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