Article

A <i>Bbs5</i> mouse model reveals pituitary cilia contributions to developmental abnormalities

2020-08-19

Abstract excerpt

Primary cilia are critical sensory and signaling compartments present on most mammalian cell types. These specialized structures require a unique signaling protein composition relative to the rest of the cell to carry out their functions. Defects in ciliary structure and signaling result in a broad group of disorders collectively known as ciliopathies. One ciliopathy, Bardet-Biedl Syndrome (BBS; OMIM 209900), pres...

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Literature Corpus work: b9cff6c0-356c-5566-9495-b84b4a172f07
DOI: 10.1101/2020.08.18.256537

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