Article

Successful treatment of an anti-MDA5 antibody-positive Juvenile Dermatomyositis patient with refractory interstitial lung disease using tofacitinib

2024-10-23

Abstract excerpt

<title>Abstract</title> <p>Juvenile dermatomyositis (JDM) is a rare autoimmune disorder affecting children, mainly characterized by skin rash and muscle weakness (1). Anti-MDA5 antibody-positive JDM represents a distinct phenotype of disease with a high risk of developing life-threatening progressive interstitial lung disease (ILD)(2). The pivotal role of the type I interferon (IFN) pathway in the pathogenesis of...

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Literature Corpus work: fd79564d-6744-5e38-9edd-bb2c51f0d5e3
DOI: 10.21203/rs.3.rs-4973421/v1

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