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Article

Anti-MDA5 autoantibodies in juvenile dermatomyositis identify a distinct clinical phenotype: a prospective cohort study.

Arthritis research & therapy - 2 Jul 2014

Tansley Sarah L, Betteridge Zoe E, Gunawardena Harsha, Jacques Thomas S, Owens Catherine M, Pilkington Clarissa, Arnold Katie, Yasin Shireena, Moraitis Elena, Wedderburn Lucy R, McHugh Neil J

Abstract excerpt

INTRODUCTION: The aim of this study was to define the frequency and associated clinical phenotype of anti-MDA5 autoantibodies in a large UK based, predominantly Caucasian, cohort of patients with juvenile dermatomyositis (JDM). METHODS: Serum samples and clinical data were obtained from 285 patients with JDM recruited to the UK Juvenile Dermatomyositis Cohort and Biomarker Study. The presence of anti-MDA5...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24989778
DOI: 10.1186/ar4600
PMCID: PMC4227127

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Source receipt: pubmed, retrieved 7 Sept 2026.

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