Article
Genome graphs detect human polymorphisms in active epigenomic state during influenza infection
2021-10-01
Abstract excerpt
Genetic variants, including mobile element insertions (MEIs), are known to impact the epigenome. We hypothesized that the use of a genome graph, which encapsulates genetic diversity, could reveal missing epigenomic signal. Given the contributions of mobile elements to the evolution of primate innate immunity, we tested this in monocyte-derived macrophages obtained from 35 individuals before and after Influenza vi...
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Identifiers and source
- Literature Corpus work
- fd47cc64-53b5-57fc-b7b5-524c5b2f6c72
- DOI
- 10.1101/2021.09.29.462206