Article

Histopathological Landscape of Molecular Genetics and Clinical Determinants in MDS Patients

2020-05-03

Abstract excerpt

In myelodysplastic syndrome (MDS), bone marrow (BM) histopathology is visually assessed to identify dysplastic cellular morphology, cellularity, and blast excess. Yet, many morphological findings elude the human eye. Here, we extracted visual features of 236 MDS, 87 MDS/MPN, and 10 control BM biopsies with convolutional neural networks. Unsupervised analysis distinguished underlying correlations between tissue com...

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Literature Corpus work: fceddad7-c5f4-541e-82d7-7ae10f418925
DOI: 10.1101/2020.05.03.073858

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