Article

Screening of metabolism-disrupting chemicals on pancreatic α-cells using in vitro methods

2022-11-07

Abstract excerpt

Metabolism-disrupting chemicals (MDCs) are endocrine disruptors with obesogenic and/or diabetogenic action. There is mounting evidence linking exposure to MDCs to increased susceptibility to diabetes. Despite the important role of glucagon in glucose homeostasis, there is little information on the effects of MDCs on α-cells. Furthermore, there are no methods to identify and test MDCs with the potential to alter α-...

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Literature Corpus work: fcc36380-765c-5260-af2b-a251e7b4057b
DOI: 10.1101/2022.11.07.515443

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