Article

Impact of population structure in the design of RNA-based diagnostics for antibiotic resistance in <i>Neisseria gonorrhoeae</i>

2019-01-31

Abstract excerpt

<h4>ABSTRACT</h4> Quantitative assessment of antibiotic-responsive RNA transcripts holds promise for a rapid point of care (POC) diagnostic tool for antimicrobial susceptibility testing. These assays aim to distinguish susceptible and resistant isolates by transcriptional differences upon drug exposure. However, an often-overlooked dimension of designing these tests is that the genetic diversity within a species...

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Literature Corpus work: fc9e3d1e-ad82-5a33-9bf3-d610dd971135
DOI: 10.1101/537175

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