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Investigating the Mitochondria-Related Mechanisms of Ligustri Lucidi Fructus in Treating Diabetic Nephropathy: A Combined Approach of Network Pharmacology, Transcriptomics, and Experimental Validation

2026-01-09

Abstract excerpt

Mitochondrial dysfunction and excessive oxidative stress within mitochondria are key pathological factors driving renal tubular injury in diabetic nephropathy (DN). While Ligustri Lucidi Fructus (LLF) is traditionally used in the treatment of DN, its precise mechanisms, particularly those involving mitochondria, remain poorly understood. This study identifies differentially expressed genes (DEGs) through different...

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Literature Corpus work
fc7b3fb9-8d92-529b-b249-ebd3c9d1ccab
DOI
10.64898/2026.01.08.698456
Open publication

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Investigating the Mitochondria-Related Mechanisms of Ligustri Lucidi Fructus in Treating Diabetic Nephropathy: A Combined Approach of Network Pharmacology, Transcriptomics, and Experimental ValidationDOI 10.64898/2026.01.08.698456
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