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Systems biology and machine learning approaches identify drug targets in diabetic nephropathy

6 Dec 2021

Abstract excerpt

Diabetic nephropathy (DN), the leading cause of end-stage renal disease, has become a massive global health burden. Despite considerable efforts, the underlying mechanisms have not yet been comprehensively understood. In this study, a systematic approach was utilized to identify the microRNA signature in DN and to introduce novel drug targets (DTs) in DN. Using microarray profiling followed by qPCR confirmation,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34873190
DOI: 10.1038/s41598-021-02282-3

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