Article
Exploration of the Mechanism of Xinjiang Rosa laxa Retz.Fruit Extract on IgA Nephropathy by Bioinformatics and Machine Learning Methods
2026-03-20
Abstract excerpt
<title>Abstract</title> <p>This study aimed to elucidate the core therapeutic targets and mechanisms of action of rosehip extract (FRLE) in IgA nephropathy (IgAN) by integrating bioinformatics, machine learning, and computational simulation techniques to simultaneously analyze the therapeutic effects of FRLE on IgAN. Through screening differentially expressed genes in IgAN patients and identifying potential targe...
Topics
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- Berberine and alkaloids research
- Chronic Kidney Disease and Diabetes
- Medicinal Plants and Bioactive Compounds
- Metabolomics and Mass Spectrometry Studies
- Natural Antidiabetic Agents Studies
- Pharmacogenetics and Drug Metabolism
- Pharmacological Effects of Natural Compounds
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- 76416c8e-0123-5e5e-8497-6fffef961e77
- DOI
- 10.21203/rs.3.rs-9095922/v1
