Article

A Dual Loci Quality Assurance and Control Framework for Real-Time Evaluation of Signal Accuracy in Wastewater Surveillance of Pathogens with High Rates of Mutation

2023-08-15

Abstract excerpt

Wastewater surveillance of coronavirus disease 2019 (COVID-19) commonly applies reverse transcription-quantitative polymerase chain reaction (RT-qPCR) to quantify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA concentrations in wastewater over time. In most applications worldwide, maximal sensitivity and specificity of RT-qPCR has been achieved, in part, by monitoring two or more genomic loci of...

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Literature Corpus work: fc52d04d-2fa6-5dca-9c5a-a1791833e14b
DOI: 10.21203/rs.3.rs-3229049/v1

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