Article
Explaining the impact of mutations on quantification of SARS-CoV-2 in wastewater.
Scientific reports - 30 May 2024
Endo Noriko, Nihei Yoshiaki, Fujita Tomonori, Yasojima Makoto, Daigo Fumi, Takemori Hiroaki, Nakamura Masafumi, Matsuda Ryo, Sovannrlaksmy Sorn, Ihara Masaru
Abstract excerpt
Wastewater surveillance is an effective tool for monitoring community spread of COVID-19 and other diseases. Quantitative PCR (qPCR) analysis for wastewater surveillance is more susceptible to mutations in target genome regions than binary PCR analysis for clinical surveillance. The SARS-CoV-2 concentrations in wastewater estimated by N1 and N2 qPCR assays started to diverge around July 2022 in data from...
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