Article

Pan-Cancer chromatin analysis of the human vtRNA genes uncovers their association with cancer biology

2020-10-05

Abstract excerpt

The vault RNAs (vtRNAs) are a class of 84-141 nt eukaryotic non-coding RNAs transcribed by RNA polymerase III, named for their association with the conserved vault particle, a riboprotein complex whose function remains poorly understood. Of the 4 human vtRNA genes, the three clustered at locus 1, i.e. vtRNA1-1, vtRNA1-2 and vtRNA1-3, are integral components of the vault particle, while vtRNA2-1 is a more divergent...

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Literature Corpus work: fc4f737f-795c-5d8a-a42a-ba74d1c9c74c
DOI: 10.1101/2020.10.05.324723

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