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A DNA-based optical nanosensor for <i>in vivo</i> imaging of acetylcholine in the peripheral nervous system

2020-07-06

Abstract excerpt

The ability to monitor the release of neurotransmitters during synaptic transmission would significantly impact the diagnosis and treatment of neurological disease. Here, we present a DNA-based enzymatic nanosensor for quantitative detection of acetylcholine (ACh) in the peripheral nervous system of living mice. ACh nanosensors consist of DNA as a scaffold, acetylcholinesterase as a recognition component, pH-sensi...

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Literature Corpus work
fbb30e98-ded7-5be5-a2b3-eabb73bca9ee
DOI
10.1101/2020.07.06.189696
Open publication

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