Article

Direct conversion of human endothelial cells to hepatic progenitor cells

2020-10-22

Abstract excerpt

<title>Abstract</title> <p>This protocol describes direct lineage reprogramming of human endothelial cells isolated from the umbilical vein and peripheral blood into hepatic progenitor cells. These induced human hepatic progenitor cells (hiHepPCs) proliferate in long-term culture and give rise to hepatocytes and cholangiocytes as descendants. To induce hiHepPCs from endothelial cells, we first established an effi...

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Literature Corpus work: fb7e8e82-d686-50a0-ba92-3d81ac16c5d5
DOI: 10.21203/rs.3.pex-1093/v1

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