Article

Effect of RBD mutations in spike glycoprotein of SARS-CoV-2 on neutralizing IgG affinity

2021-02-01

Abstract excerpt

<h4>Background</h4> Certain mutant strains of SARS-CoV-2 are known to spread widely among humans, including the receptor binding domain (RBD) mutant, Y453F, from farmed minks, and the RBD mutant, N501Y, a mutation common to three major SARS-CoV-2 subspecies (B.1.1.7, B.1.351, and B.1.1.248). <h4>Methods</h4> We investigated the characteristics of the RBD mutants, Y453F and N501Y, using three-dimensional structural...

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Literature Corpus work: fb4d122d-8887-5fa6-a691-46b4dbef5d07
DOI: 10.1101/2021.01.28.21250577

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