Article

Effect of RBD mutations in spike glycoprotein of SARS-CoV-2 on neutralizing IgG affinity

2021-03-30

Abstract excerpt

<h4>Background: </h4> Certain mutant strains of SARS-CoV-2 are known to spread widely among humans, including the receptor binding domain (RBD) mutant, Y453F, from farmed minks, and the RBD mutant, N501Y, a mutation common to three major SARS-CoV-2 subspecies (B.1.1.7, B.1.351, and B.1.1.248). <h4>Methods:</h4> We investigated the characteristics of the RBD mutants, Y453F and N501Y, using three-dimensional structu...

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Literature Corpus work: fde30b2e-6974-5aee-b8c6-add91ff68777
DOI: 10.21203/rs.3.rs-363352/v1

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