Article

Ultrastructural Analysis of Nigrostriatal Dopaminergic Terminals in a Knockin Mouse Model of DYT1 Dystonia

2023-03-10

Abstract excerpt

DYT1 dystonia is a form of generalized dystonia associated with abnormalities in striatal dopamine release in mouse models and likely in humans. In the present study, we examined the possibility that ultrastructural changes in the morphology of nigrostriatal dopamine terminals could contribute to this neurochemical imbalance using a Serial-Block Face/Scanning Electron Microscope (SBF/SEM) and three-dimensional rec...

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Literature Corpus work: fb4241e3-fd75-567c-b4fb-641b6c3694da
DOI: 10.22541/au.167845349.99052281/v1

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