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Anti-HERV-K Drugs and Vaccines, Possible Therapies against Tumors

28 Mar 2023

Abstract excerpt

The footprint of human endogenous retroviruses (HERV), specifically HERV-K, has been found in malignancies, such as melanoma, teratocarcinoma, osteosarcoma, breast cancer, lymphoma, and ovary and prostate cancers. HERV-K is characterized as the most biologically active HERV due to possession of open reading frames (ORF) for all Gag, Pol, and Env genes, which enables it to be more infective and obstructive towards...

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PMID: 37112663
DOI: 10.3390/vaccines11040751

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