Article

Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells

2022-05-16

Abstract excerpt

<h4>Background</h4> Neuronopathic Gaucher Disease (nGD) is a rare neurodegenerative disorder caused by biallelic mutations in Gba , and buildup of glycosphingolipids in lysosomes. Neuronal injury and cell death are prominent pathological features, however the role of Gba in individual cell types and involvement of microglia, blood derived macrophages and immune infiltrates in nGD pathology remains enigmatic. <...

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Literature Corpus work: facb4cb5-0730-5718-b258-779796592714
DOI: 10.1101/2022.05.13.491834

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