Article

AI-powered integration of multi-source data for TAA discovery to accelerate ADC and TCE drug development (I): TAA Target Identification and Prioritization

2025-05-08

Abstract excerpt

The advancement of T-cell engagers (TCEs) and antibody-drug conjugates (ADCs) has been hindered by fragmented data landscapes. This paper, the first in a series, introduces an AI-driven framework specifically for tumor-associated antigen (TAA) target identification and prioritization, a critical initial step in TCE and ADC development. Our framework integrates diverse datasets— including multi-omics repositories a...

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Literature Corpus work: fa9a1531-6fca-534c-a459-abdf4387e581
DOI: 10.1101/2025.05.06.652559

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