Article

Integration of multi-source gene interaction networks and omics data with graph attention networks to identify novel disease genes

2023-12-05

Abstract excerpt

The pathogenesis of diseases is closely associated with genes, and the discovery of disease genes holds significant importance for understanding disease mechanisms and designing targeted therapeutics. However, biological validation of all genes for diseases is expensive and challenging. In this study, we propose DGP-AMIO, a computational method based on graph attention networks, to rank all unknown genes and ident...

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Literature Corpus work: 493c5592-baa6-5425-b59b-f272cf42053d
DOI: 10.1101/2023.12.03.569371

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