Article

<i>KALRN</i> Mutations Promote Anti-tumor Immunity and Immunotherapy Response in Cancer

2020-01-29

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> KALRN (kalirin RhoGEF kinase) is mutated in a wide range of cancers. Nevertheless, the association between KALRN mutations and the pathogenesis of cancer remains unexplored. The identification of biomarkers for cancer immunotherapy response is important considering that immunotherapies show beneficial effects only in a subset of cancer patients. <h4>Methods</h4> We explor...

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Literature Corpus work: fa3d37ab-f2c6-5c6c-91ba-265ac8859fde
DOI: 10.1101/2020.01.28.922682

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