Article

LFSPROShiny: an interactive R/Shiny app for prediction and visualization of cancer risks in families with deleterious germline<i>TP53</i>mutations

2023-08-15

Abstract excerpt

<h4>Purpose</h4> LFSPRO is an R library that implements risk prediction models for Li-Fraumeni syndrome (LFS), a genetic disorder characterized by deleterious germline mutations in the TP53 gene. To facilitate the use of these models in clinics, we developed LFSPROShiny, an interactive R/Shiny interface of LFSPRO that allows genetic counselors (GCs) to perform risk predictions without any programming components, a...

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Literature Corpus work: fa1b83b8-da54-572c-b8ea-f619016d9670
DOI: 10.1101/2023.08.11.23293956

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