Article

FLUAV RAM-IGIP: A modified live influenza virus vaccine that enhances humoral and mucosal responses against influenza

2024-01-24

Abstract excerpt

<h4>ABSTRACT</h4> Current influenza A vaccines fall short, leaving both humans and animals vulnerable. To address this issue, we have developed attenuated modified live virus (MLV) vaccines against influenza using genome rearrangement techniques targeting the internal gene segments of FLUAV. The rearranged M2 (RAM) strategy involves cloning the M2 ORF downstream of the PB1 ORF in segment 2 and incorporating multi...

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Literature Corpus work: f9c54d8a-fc1c-50c7-9a3b-f3eb01eb12c7
DOI: 10.1101/2024.01.23.576908

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