Article
Development of an Alternative Modified Live Influenza B Virus Vaccine.
Journal of virology - 15 Jun 2017
Santos Jefferson J S, Finch Courtney, Sutton Troy, Obadan Adebimpe, Aguirre Isabel, Wan Zhimin, Lopez Diego, Geiger Ginger, Gonzalez-Reiche Ana Silvia, Ferreri Lucas, Perez Daniel R
Abstract excerpt
Influenza B virus (IBV) is considered a major human pathogen, responsible for seasonal epidemics of acute respiratory illness. Two antigenically distinct IBV hemagglutinin (HA) lineages cocirculate worldwide with little cross-reactivity. Live attenuated influenza virus (LAIV) vaccines have been shown to provide better cross-protective immune responses than inactivated vaccines by eliciting local mucosal immunity...
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