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miRNA-126-3p carried by human umbilical cord mesenchymal stem cell enhances endothelial function through exosome-mediated mechanisms in vitro and attenuates vein grafts neointimal formation in vivo

2020-10-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>The aim of this study was to determine whether the combination of MSC implantation with miRNA-126-3p overexpression would further improve the surgical results after vein grafting.<bold>Methods: </bold>hucMSCs and HUVECs were isolated from human umbilical cords and characterized by a series of experiments. Lentivirus vector encoding miRNA-126-3p was transfected i...

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Literature Corpus work
f9bf1af9-bdf6-51c9-8c71-129e4d082624
DOI
10.21203/rs.3.rs-64060/v2
Open publication

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