Article

Therapeutic ability of extracellular vesicles derived from angio-miRNA-modified mesenchymal stromal cells in ischemic animal models

2025-01-29

Abstract excerpt

<h4>Background</h4> Regenerative therapy using extracellular vesicles (EVs) is expected to be an option for supportive therapy of chronic limb-threatening ischemia. In this study, we examined the angiogenic potential of EVs derived from genetically modified MSCs, focusing on the angio-miRNAs in these vesicles. <h4>Methods</h4> Bone marrow mesenchymal stromal cells (BM-MSCs) were transfected with a lentiviral vec...

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Literature Corpus work: 3dea369d-0fd6-5ea7-951d-a7d3ce280f4d
DOI: 10.1101/2025.01.27.635184

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