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Merkel cell polyomavirus regulates miR183 cluster and piR62011 in Merkel cell carcinoma

2022-01-20

Abstract excerpt

<h4>ABSTRACT</h4> Merkel cell carcinoma (MCC) is a rare, aggressive skin cancer, a major subset of which is caused by the clonal integration of Merkel Cell Polyomavirus (MCV). Recent studies by Cheng et al. (2017) reported that virus-derived small T antigen protein-bound EP400 complex drives expression of genes essential for cellular transformation. On close analysis of their ChIP-Seq data, we uncovered that the...

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Literature Corpus work
f9b81802-78ce-5830-b4a9-f0ee4c440d49
DOI
10.1101/2022.01.18.476776
Open publication

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