Article
Unveiling the Cellular and Molecular Mechanisms of Diabetic Retinopathy with Human Retinal Organoids
2025-02-26
Abstract excerpt
Diabetic retinopathy (DR) is a leading cause of vision impairment worldwide, driven by chronic hyperglycaemia and its complex metabolic consequences. While animal models have been widely used to study DR, they often fail to replicate the physiology of human retina. To address this limitation, we employed human retinal organoids as a model to study the effects of hyperglycaemia across various stages of retinal diff...
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Identifiers and source
- Literature Corpus work
- f9b05059-7ee4-53f0-89b1-f202ecdc9cbc
- DOI
- 10.1101/2025.02.24.639921