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Induction of a Müller Glial Cell–Specific Protective Pathway Safeguards the Retina From Diabetes-Induced Damage

24 Oct 2024

Abstract excerpt

Diabetes can lead to cell type-specific responses in the retina, including vascular lesions, glial dysfunction, and neurodegeneration, all of which contribute to retinopathy. However, the molecular mechanisms underlying these cell type-specific responses, and the cell types that are sensitive to diabetes have not been fully elucidated. Using single-cell transcriptomics, we profiled the transcriptional changes...

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PMID: 39446557
DOI: 10.2337/db24-0199

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