Article

A metabolite extracted from <i>E. coli</i> suppresses tau aggregation

2025-10-31

Abstract excerpt

Tau aggregation is a key pathological feature of neurodegenerative diseases termed tauopathies. Identifying the various cellular factors that function to prevent tau aggregation in cells can generate key insights into how to mitigate diseases associated with protein misfolding. During an investigation into developing purification methods for the protein tau, we observed that isolates of E. coli lysate prevented h...

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Identifiers and source

Literature Corpus work: f9a5f82c-b693-5332-8366-d9929e007142
DOI: 10.1101/2025.10.30.684975

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