Article

Bardoxolone methyl improves non-alcoholic steatohepatitis through inhibition of macrophage infiltration.

2023-10-24

Abstract excerpt

<h4>Background: </h4> and purpose: Bardoxolone methyl (2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid methyl ester, CDDO-Me) is a potent activator of nuclear factor erythroid 2-related factor (Nrf)2, which induces anti-oxidative-associated genes. CDDO-Me is known to exert protective effects against chronic inflammatory diseases in the kidney and lungs. However, its pharmacological effects on non-alcoholic steat...

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Literature Corpus work: f95c2657-5110-5cff-ae36-3a00b9ef589d
DOI: 10.22541/au.169815277.77043092/v1

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