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Article

Unbinned contigs expand known diversity in the global microbiome.

Nature microbiology - 1 May 2026

Prasoodanan Pk Vishnu, Maistrenko Oleksandr M, Fullam Anthony, Mende Daniel R, Kartal Ece, Coelho Luis Pedro, Spang Anja, Bork Peer, Schmidt Thomas S B

Abstract excerpt

The ongoing census of microbial life is hampered by disparate sampling across Earth's habitats, challenges in isolating uncultivated organisms, limited resolution in taxonomic marker gene amplicons and incomplete recovery of metagenome-assembled genomes. Here we quantify discoverable Bacterial and Archaeal diversity in a comprehensive, curated cross-habitat dataset of 92,187 publicly available metagenomes....

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Identifiers

PMID: 41933201
DOI: 10.1038/s41564-026-02314-6
PMCID: PMC13171631

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