Article

Chromatin modifiers and recombination factors promote a telomere fold-back structure, that is lost during replicative senescence

2020-01-13

Abstract excerpt

Telomeres adopt a lariat conformation and hence, engage in long and short distance intra-chromosome interactions. Budding yeast telomeres were proposed to fold back into subtelomeric regions, but a robust assay to quantitatively characterize this structure has been lacking. Therefore, it is not well understood how the interactions between telomeres and non-telomeric regions are established and regulated. We employ...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f9527e5b-f766-538d-b24c-b594041ec31c
DOI: 10.1101/2020.01.13.904086

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Chromatin modifiers and recombination factors promote a telomere fold-back structure, that is lost during replicative senescenceDOI 10.1101/2020.01.13.904086Read

Rif2 promotes a telomere fold-back structure through Rpd3L recruitment in budding yeast.Semantic proximity Read

To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand BreaksSemantic proximity Read

Abrupt telomere losses and reduced end-resection can explain accelerated senescence of Smc5/6 mutants lacking telomerase.Semantic proximity Read

Rif1 and Exo1 regulate the genomic instability following telomere losses.Semantic proximity Read

A quantitative assay for telomere protection in Saccharomyces cerevisiae.Semantic proximity Read

Linear chromosome maintenance in the absence of essential telomere-capping proteins.Semantic proximity Read

Saccharomyces cerevisiae as a Model to Study Replicative Senescence Triggered by Telomere ShorteningSemantic proximity Read

Evolution of CST function in telomere maintenanceSemantic proximity Read

A beginning of the end: new insights into the functional organization of telomeresSemantic proximity Read

Sumoylation and the structural maintenance of chromosomes (Smc) 5/6 complex slow senescence through recombination intermediate resolution.Semantic proximity Read

All things must end: telomere dynamics in yeast.Semantic proximity Read

Histone Modifications and the Maintenance of Telomere IntegritySemantic proximity Read