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Evolutionary pressures shape soft tissue sarcoma development and radiotherapy response

2023-09-26

Abstract excerpt

<title>Abstract</title> <p>Evolutionary pressures play a key role in tumorigenesis, progression, and response to therapy. However, the selection pressures and subclonal dynamics of soft tissue sarcomas during their natural history remain to be defined. Additionally, although radiotherapy plays a crucial role in obtaining local control for many solid tumors, the effect of radiation on tumor evolution has been chal...

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Literature Corpus work
f92fcf27-fac4-505f-b253-5356bbd6f3e0
DOI
10.21203/rs.3.rs-3332073/v1
Open publication

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