Article
Identification of small ubiquitin-related modifier (SUMO)-related genes-based biomarkers in Alzheimer's disease based on bioinformatics analysis
2025-10-28
Abstract excerpt
<title>Abstract</title> <p> Background To explore the role of small ubiquitin-related modifier (SUMO) in Alzheimer's disease (AD) and its pathogenesis, bioinformatics was used to search for SUMO-related genes (SRGs)-based biomarkers. Methods Datasets related to AD (GSE140831, GSE63060), a dementia dataset (GSE140830), and 189 SRGs were retrieved from public databases. Candidate genes were identified by intersect...
Topics
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- Alzheimer's disease research and treatments
- ATP Synthase and ATPases Research
- Cholinesterase and Neurodegenerative Diseases
- Histone Deacetylase Inhibitors Research
- MicroRNA in disease regulation
- Mitochondrial Function and Pathology
- Neuroinflammation and Neurodegeneration Mechanisms
- Nuclear Receptors and Signaling
Identifiers and source
- Literature Corpus work
- f92e188f-1118-511b-8f4e-20bf368a3785
- DOI
- 10.21203/rs.3.rs-6983921/v1
