Analysis of genes associated with Alzheimer's disease and endoplasmic reticulum stress

Abstract excerpt

<title>Abstract</title> <p><bold>Objecitve </bold>Endoplasmic reticulum (ER) stress can activate the unfolded protein response (UPR), and sustained activation of UPR is closely associated with inflammation and neuronal dysfunction, ultimately leading to neurodegeneration. This study aims to identify potential targets related to ER stress, aiming to provide new insights into the treatment of Alzheimer's disease (A...

Topics

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• Alzheimer's disease research and treatments
• Amyotrophic Lateral Sclerosis Research
• ATP Synthase and ATPases Research
• Bioinformatics and Genomic Networks
• GDF15 and Related Biomarkers
• Mitochondrial Function and Pathology
• Neuroinflammation and Neurodegeneration Mechanisms
• Nuclear Receptors and Signaling

Identifiers and source

Literature Corpus work

2be4f134-fe82-5662-83c7-a3bc738d7679

DOI

10.21203/rs.3.rs-4334229/v1