Article

Opposing diet, microbiome and metabolite mechanisms regulate inflammatory bowel disease in a genetically susceptible host

2022-04-03

Abstract excerpt

<h4>Summary</h4> Inflammatory bowel diseases (IBDs) are chronic conditions characterized by periods of spontaneous intestinal inflammation and are increasing in industrialized populations. Combined with host genetics, diet and gut bacteria are thought to contribute prominently to IBDs, but mechanisms are still emerging. In mice lacking the IBD-associated cytokine, Interleukin-10, we show that low dietary fiber pr...

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Literature Corpus work: 3d317ca4-38dd-5139-a28f-6d616ff002b1
DOI: 10.1101/2022.04.03.486886

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