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Time-course RNA sequencing reveals high similarity in mRNAome between hepatic stellate cells activated by agalactosyl IgG and TGF-β1

2024-11-11

Abstract excerpt

<title>Abstract</title> <p>Previous studies have demonstrated the clinical relevance of aberrant serum immunoglobulin G (IgG) <italic>N</italic>-glycomic profiles in liver fibrosis and the pathogenic effects of agalactosyl IgG on activating hepatic stellate cells (HSCs). However, the dynamics of gene expression changes during HSC activation by agalactosyl IgG remain poorly understood. We performed RNA sequencing...

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Literature Corpus work
f8a581c9-06e2-5938-996c-f92b896c003d
DOI
10.21203/rs.3.rs-5082024/v1
Open publication

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Time-course RNA sequencing reveals high similarity in mRNAome between hepatic stellate cells activated by agalactosyl IgG and TGF-β1DOI 10.21203/rs.3.rs-5082024/v1
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