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A cell atlas of human adrenal cortex development and disease

2022-12-14

Abstract excerpt

The adrenal glands synthesize and release essential steroid hormones such as cortisol and aldosterone, but the mechanisms underlying human adrenal gland development are not fully understood. Here, we combined single-cell and bulk RNA-sequencing, spatial transcriptomics, immunohistochemistry and micro-focus computed tomography to investigate key aspects of adrenal development in the first 20 weeks of gestation. We...

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Identifiers and source

Literature Corpus work
99245d9e-3133-5c91-8330-896f62dc3c63
DOI
10.1101/2022.12.13.520231
Open publication

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A cell atlas of human adrenal cortex development and diseaseDOI 10.1101/2022.12.13.520231
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