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Article

Neurodevelopmental Disorders: From Genetics to Functional Pathways.

Trends in neurosciences - 1 Aug 2020

Parenti Ilaria, Rabaneda Luis G, Schoen Hanna, Novarino Gaia

Abstract excerpt

Neurodevelopmental disorders (NDDs) are a class of disorders affecting brain development and function and are characterized by wide genetic and clinical variability. In this review, we discuss the multiple factors that influence the clinical presentation of NDDs, with particular attention to gene vulnerability, mutational load, and the two-hit model. Despite the complex architecture of mutational events...

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Identifiers

PMID: 32507511
DOI: 10.1016/j.tins.2020.05.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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