Back to search

Article

Direct targeting of SLC7A11 by miR-143-3p promotes ferroptosis and suppresses malignancy in cervical squamous cell carcinoma

2026-08-20

Abstract excerpt

<title>Abstract</title> <p>Background Cervical cancer is a major cause of cancer-related mortality among women, and current therapeutic options remain limited. Emerging evidence suggests that targeted induction of ferroptosis represents a promising strategy for cancer management. Nevertheless, the role and underlying mechanisms of ferroptosis in early-stage cervical squamous cell carcinoma (SCC) remain unclear....

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f83eb45e-1a3f-5c2e-8937-aad753135a31
DOI
10.21203/rs.3.rs-10336712/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 10 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Direct targeting of SLC7A11 by miR-143-3p promotes ferroptosis and suppresses malignancy in cervical squamous cell carcinomaDOI 10.21203/rs.3.rs-10336712/v1
HPV16 integration regulates ferroptosis resistance via the c-Myc/miR-142-5p/HOXA5/SLC7A11 axis during cervical carcinogenesisSemantic proximity
Down regulation of miR-143 is related with tumor size, lymph node metastasis and HPV16 infection in cervical squamous cancer.Semantic proximity
MicroRNA-4735-3p Facilitates Ferroptosis in Clear Cell Renal Cell Carcinoma by Targeting SLC40A1Semantic proximity
A Functional Polymorphism in the Promoter of MiR-143/145 Is Associated With the Risk of Cervical Squamous Cell Carcinoma in Chinese Women: A Case-Control Study.Semantic proximity
SAT1-Mediated Spermidine Metabolism Drives Ferroptosis in Cervical CancerSemantic proximity
Association between the rs3733846 in the flanking region of miR-143/145 and risk of cervical squamous cell carcinoma.Semantic proximity
The cluster of miR-143 and miR-145 affects the risk for esophageal squamous cell carcinoma through co-regulating fascin homolog 1.Semantic proximity
Down-Regulation of <i>SLC8A1</i> as a Putative Apoptosis Evasion Mechanism by Modulation of Calcium Levels in Penile CarcinomaSemantic proximity
MicroRNA‐141‐3p regulates cellular proliferation, migration, and invasion in esophageal cancer by targeting tuberous sclerosis complex 1Semantic proximity
[miR-143 inhibits cell proliferation through targeted regulating the expression of K-ras gene in HeLa cells].Semantic proximity
Select a neighboring publication to make it the new centre.