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Article

Regulation of sugar transport and metabolism by the Candida albicans Rgt1 transcriptional repressor.

Yeast (Chichester, England) - 1 Oct 2007

Sexton Jessica A, Brown Victoria, Johnston Mark

Abstract excerpt

The ability of the fungal pathogen Candida albicans to cause systemic infections depends in part on the function of Hgt4, a cell surface sugar sensor. The orthologues of Hgt4 in Saccharomyces cerevisiae, Snf3 and Rgt2, initiate a signalling cascade that inactivates Rgt1, a transcriptional repressor of genes encoding hexose transporters. To determine whether Hgt4 functions similarly through the C. albicans...

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Identifiers

PMID: 17605131
DOI: 10.1002/yea.1514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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