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Hybrid capture-based sequencing enables unbiased recovery of SAR-CoV-2 genomes from fecal samples and characterization of the dynamics of intra-host variants

2020-08-01

Abstract excerpt

<h4>Background</h4> In response to the current COVID-19 pandemic, it is crucial to understand the origin, transmission, and evolution of SARS-CoV-2, which relies on close surveillance of genomic diversity in clinical samples. Although the mutation at the population level had been extensively investigated, how the mutations evolve at the individual level is largely unknown, partly due to the difficulty of obtainin...

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Literature Corpus work
f77a78ad-ac15-576e-b023-848d4444cf85
DOI
10.1101/2020.07.30.230102
Open publication

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Hybrid capture-based sequencing enables unbiased recovery of SAR-CoV-2 genomes from fecal samples and characterization of the dynamics of intra-host variantsDOI 10.1101/2020.07.30.230102
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